This paper calls for an integrated water and food security management in eight Eastern and Southern African countries—Ethiopia, Kenya, Malawi, Mozambique, Somalia, South Sudan, Zambia, and Zimbabwe. These countries, identified as Hunger Hotspots for 2025 and among the 30 most water insecure globally, are also experiencing the severe impacts of climate variability. The paper strongly recommends that multilateral bodies, governments, donors, and the private sector implement sustainable adaptation and mitigation measures—such as strengthening national hydro-meteorological forecasting systems, increasing investment in anticipatory action, ensuring access to climate finance etc. to tackle the root causes of these crises. Furthermore, it also provides insights into effective water management practices that can help national governments and policymakers adopt comprehensive policies, ultimately improving governance to tackle the triple crises of water, food and climate.